Billion To One

We are ONE team,
working towards ONE goal to

detect disease

ONE molecule at a time.

Closeup of BTO lab equipment and an animation showing a grid of letters A T C and G with the focus moving to different letters in the grid

One in a
Few Billion

There are three billion letters, three billion nucleotides that make up our genome. Our proprietary technology has the ability to detect and quantify disease at single base-pair resolution. Our name speaks to this unique technology, and we are focused on applying it to various disease states to help more patients.

Mission, Vision, Values

At the Forefront of
Disease Detection

woman working in a lab

Our proprietary Quantitative Counting Templates, or QCTs™, power our ability to detect and measure tiny and sparse disease-related DNA fragments, or molecules, at the single base-pair level. Several common and severe recessive conditions screened for prenatally can be caused by single-base pair alterations.
Our QCT technology enables quantifying these tiny variations using cell-free DNA. We believe this quantification will open the door to exponential improvements in prenatal screening, liquid biopsy, and beyond.

Moving Prenatal Screening and Oncology Testing Forward

Prenatal closeup on pregnant woman's stomach with her hands lovingly held above and below her belly.

We assess fetal risk for recessive conditions and aneuploidies from maternal blood.
UNITY Screen™ includes a carrier screen as well as a single-gene (for recessive conditions) and aneuploidy NIPT and only requires a maternal blood draw at 10+ weeks to assess fetal risk. No paternal sample needed.

Explore Prenatal
Oncology gloved hand holding a test tube with blood

Northstar Select™ and Northstar Response™ are now available for commercial use.
Northstar Select™ helps determine the most appropriate first line therapy, and Northstar Response™ helps monitor if the therapy is working.

Explore Oncology

Coupling Careers with Great Culture

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“BillionToOne’s leadership values growth of the company’s employees and equality among peers.”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“I love BillionToOne’s culture, everyone is so welcoming and always open to lend a helping hand.”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“We have a very strong culture of cross-departmental teamwork. Everyone here cares about making an impact!”

Three employees - a man and two women, one with bright scarlet hair - standing at a computer and working together in a Billion To One lab

“I love being able to introduce the latest and greatest technology to Women’s Health providers that will improve their knowledge on each pregnancy and give babies the best shot at healthy beginnings!”

Coupling Careers with Great Culture

What unites our team and drives us forward is one goal of making molecular testing more accurate, efficient, and accessible to all. This special group of bright and talented people is improving healthcare. If this appeals to you, consider joining us.

Leading with Passion and Purpose

Co-founders Oguzhan Atay, Ph.D., and David Tsao, Ph.D., and our team of engineers, scientists, and industry experts care deeply about every sample that comes into our lab.

Collage of three photos: headshots of the two founders and one of a man and woman at a whiteboard

News & Media

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Press Releases

BILLIONTOONE ANNOUNCES ROSS TAYLOR AS CHIEF FINANCIAL OFFICER

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Press Releases

BillionToOne to Present at the 42nd Annual J.P. Morgan Healthcare Conference

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Press Releases

BillionToOne Announces Global Collaboration to Provide its UNITY Fetal Antigen™ Clinical Trial Assay in Johnson & Johnson Phase 3 Clinical Trial of Nipocalimab in Hemolytic Disease of the Fetus and Newborn

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Media Coverage

UNITY Fetal Risk Screen has earned a spot in AJHG’s Genomic Medicine Year in Review: 2023, recognized as a top 10 key advancement in applying genomics to clinical care.

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Media Coverage

BillionToOne recognized as one of the most promising digital health companies of 2023 by CB Insights

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Press Releases

BillionToOne Announces Clinical Outcomes Data for UNITY Fetal Risk™ Screen, Demonstrating Exceptional Accuracy in General Pregnancy Population

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Press Releases

BillionToOne Publishes UNITY Fetal RhD and Fetal Antigen NIPT Clinical Validity Demonstrating >99.9% Accuracy

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Media Coverage

BillionToOne, Inc., Secures Landmark Win in Lawsuit Against CDPH’s PNS Program in Order to Maintain Patient and Provider Choice Regarding Cell-free DNA Screening for Trisomy 21, 18, and 13

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Press Releases

BillionToOne appoints Dr. Gary Palmer as Chief Medical Officer, Oncology; Launches Northstar Select™ and Northstar Response™ Liquid Biopsy Assays for Commercial Use

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Press Releases

BillionToOne Announces $48.5M Additional Capital Raise and $35M Upsized Term Loan Facility, Demonstrating Investor and Lender Confidence in the Company’s Rapid Growth

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